An ameloblastic fibroma is a fibroma of the ameloblastic tissue, that is, an odontogenic tumor arising from the enamel organ or dental lamina. It may be either. Ameloblastic fibroma, is a mixed odontogenic tumor, which commonly affects young children under the age of 20 years, with the mandibular premolar-molar. ameloblastic fibroma in a 9-year-old boy has been presented along with a review of the literature. The tumor responded to conservative surgical treatment.

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Ameloblastic fibroma is a true-mixed neoplasm of odontogenic origin with both epithelial and mesenchymal tissues [ 4 ]. AF was first described by Krause in Both the swellings exhibited gradual increase in size with evidence of nasal blockage Figure 1.

Ameloblastic fibroma

An ameloblastic fibroma is a fibroma of the ameloblastic tissue, that is, an odontogenic tumor arising from the enamel organ or dental lamina. No atypia was observed.

They are usually encountered in children, emphasizing it as an important diagnostic consideration. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3. Introduction Ameloblastic fibromas AFs are a rare variety of benign odontogenic tumors composed of proliferating odontogenic epithelium embedded in a cellular ectomesenchymal tissue resembling dental papilla [ 1 ].

Footnotes The opinions and assertions expressed herein are those of the author and are not to be construed as official or representing the views of the Department of the Navy or the Department of Defense.


Ameloblastic fibroma, ameloblastic fibro- odontoma, and odontoma. Cortical expansion may or may not be discernable on plane film.

Ameloblastic fibroma: A rare case appearing as a mixed radiographic image

A careful treatment planning is necessary considering their recurrence rate and ability to undergo malignant transformation.

We herein describe a massive AF involving mandible in a year-old female patient, suggestive of the neoplastic variant, with a special reference to its aspiration cytologic findings. Amelpblastic epithelium-rich odontogenic fibroma shows a variable amount of inactive odontogenic epithelial islands 6whereas the ameloblastic fibroma presents islands and strings of neoplastic epithelial cells, as occurred in this case. Surgical excision or thorough curettage with removal of affected teeth is the treatment of choice [ 12 ].

Pathology Outlines – Benign tumors / tumor-like conditions: ameloblastic fibroma

Despite the asymptomatic cases of AF usually appear as an unilocular radiolucency 4the present case was characterized as multilocular mixed image. Abstract Ameloblastic fibroma AF is a benign tumor of mixed odontogenic origin, which affects predominantly young individuals.

Thin septa were observed within lesion. The amount and density of the epithelial component may vary from region to region fibgoma the same tumor. A survey of cases from the Armed Forces Institute of Pathology. On palpation, the swelling was slightly tender and no abnormality was detected in the adjacent teeth.

Males show a slightly higher prediction than females M: The epithelial islands, nests, and strands were composed of peripheral tall columnar hyperchromatic cells exhibiting reversal of polarity and loosely arranged central cells having angular to spindle shape. The patient is currently under periodical clinical and radiographic follow up, with no signs of tumor recurrence 30 months after treatment.


The epithelial component is arranged in thin branching cords or small nests with scanty cytoplasm and basophilic nuclei, while stellate reticulum like cells are common in larger nests. However, most of the cases of AFs are encountered as an incidental finding [ 910 ] reiterating their radiographic significance in the differential diagnosis with entities such as dentigerous cyst, ameloblastoma, odontogenic keratocyst, and ameloblastic fibrosarcoma [ 1112 ].

Hyaline-like tissue is also seen adjacent to the epithelial strands and islands [ Figure 2 ].

Radiographically, AF appears as a well-defined unilocular or multilocular radiolucent image with a mean size of 4. Calcifying epithelial odontogenic tumour: It was interesting to note that both the epithelial islands and connective tissue stroma revealed high cellularity when compared with the conventional lesions of AF. Footnotes Source of Fkbroma Because of AF is often associated with non-erupted amelloblastic, it may initially be interpreted as a dentigerous cyst 12.

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The mucosa over the swelling was normal, except for slight blanching due to expansion of the buccal cortical plate. No tumor recurred up to 30 months after treatment.